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  • Author : Hoàng Thị Ngọc Hà, Hoàng Trung Hiếu, Hà Thị Hiền, Văn Nữ Thuỳ Linh, Nguyễn Thị Thanh Nhi, Trần Thị Sông Hương, Vũ Vân Anh, Bùi Thị Huyền, Trần Bá Kiên, Ngô Nguyễn Quỳnh Anh, Vincent Nguyễn.
  • Status : Published
  • Publish : Journal of Community Medicine, 2025, Vol. 66, No. 1
  • Category : Scientific publications

Description of Organic Synthesis

Advanced breast cancer prevention plays a crucial role in early detection, prevention, and effective treatment, reducing mortality, improving quality of life, and extending healthy lifespan for women. According to Globocan 2022, the incidence of breast cancer in Vietnam is very high, with a trend toward younger age, along with a significant mortality rate (8.3%). The aim of this article is to review the literature related to proactive health care to support women in advanced breast cancer prevention.
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This article is based on a review and analysis of in-depth materials regarding breast cancer screening and prevention recommendations from reputable organizations such as the American College of Radiology (ACR), the National Comprehensive Cancer Network (NCCN), as well as guidelines from Japan, China, and the Ministry of Health of Vietnam. Additionally, the article references Peter Attia’s book (2023), focusing on future medical trends under the concept of Medicine 3.0.

The search process used keywords such as “breast cancer,” “prevention,” “Medicine 3.0,” “5P model,” “risk factor,” and “healthspan.” Selected materials were based on relevance and reliability, concentrating on four main areas: (1) the effectiveness and limitations of screening methods, (2) breast cancer prevention strategies and recommendations, (3) the role of proactive health care in extending healthspan, and (4) the application of Medicine 3.0 in breast cancer prevention. The analysis focused on comparing advantages and disadvantages, providing recommendations aimed at improving the effectiveness of advanced, personalized, and proactive breast cancer prevention.

Medicine 3.0: Medical trends from the past, including Medicine 1.0, 2.0, and 3.0, differ mainly in the timing of health care initiation and the objectives to be achieved. Medicine 3.0 emphasizes proactive health care, focusing on mindset, habits, and lifestyle changes to enhance “healthspan,” rather than merely extending lifespan. The key distinction is that while Medicine 2.0 typically intervenes after health issues arise, Medicine 3.0 integrates health care into daily life. This strategy is built around five core elements: physical activity, nutrition, sleep, mental health, and the appropriate use of supplements, hormones, or medications.

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(Prediction) – Breast Cancer Risk Forecasting

Breast cancer risk forecasting can begin with screening risk factors through questionnaires, genetic testing for mutations in women with a family history, and regular imaging examinations to detect early abnormal changes in the breast.
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(Prevention) – Risk Reduction

For high-risk cases, such as women with a family history or suspected breast lesions, additional recommended examinations should be guided to ensure the earliest possible cancer detection. For individuals with low to moderate risk, especially those with modifiable risk factors due to unhealthy lifestyles, it is essential to integrate proactive health care into daily life and routines according to the principles of Medicine 3.0.
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(Personalization) – Individualization

P2 solutions must be planned and implemented based on the principles of individualization and optimization for each participating woman. Risk factor questionnaires and genetic tests should be used to personalize prevention strategies, specifically in stratifying risk, assessing current status, and evaluating the feasibility for each woman.
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(Participation) – Engagement

Provide information on support resources for women at high risk of breast cancer. Enhance women’s engagement in breast cancer screening and prevention programs. Emphasize the role of women in performing self-breast exams at home and undergoing regular breast ultrasounds at local health facilities to enable early detection of breast cancer.
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(Participation) – Involvement

Preventive care plans are developed based on screening results of genetics, biomarkers, lifestyle indices, and individual body composition, while integrating environmental information to ensure accuracy and suitability for each person’s specific physiological needs.
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